Iron and ROS control of the DownSTream mRNA decay pathway is essential for plant fitness

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Iron and ROS control of the DownSTream mRNA decay pathway is essential for plant fitness.

A new regulatory pathway involved in plant response to oxidative stress was revealed using the iron-induced Arabidopsis ferritin AtFER1 as a model. Using pharmacological and genetic approaches, the DownSTream (DST) cis-acting element in the 3'-untranslated region of the AtFER1 mRNA was shown to be involved in the degradation of this transcript, and oxidative stress triggers this destabilization...

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ژورنال

عنوان ژورنال: The EMBO Journal

سال: 2011

ISSN: 0261-4189

DOI: 10.1038/emboj.2011.341